Chip are you making an exaggeration here to make a point?
Nope. That's my routine, and once per hour is not an exagerration. My first mate does not drive the truck when pulling the trailer, so except for moral support, I'm on my own. I've driven solo as many as 16 hours in one day, though a "normal" day is usually around 12. Lots of coffee and caffeinated soda, so frequent bathroom breaks are a necessity anyway. At 6' 220 lbs, with a marginal back and bad shoulder, I've yet to find a comfortable drivers' seat for long distances, so hour is pretty much my limit between stretch breaks as well. The way I usually time it is to drive about 45 minutes, then begin looking for a rest area. It usually works out to just over an hour. On a "short hop" of a couple hundred miles or so, I might stretch it to 90 minutes or rarely, two hours, but absolutely no more. If I'm not on the Interstate, grocery store or WalMart parking lots are good, but I'll even pull over onto a wide shoulder and set the flashers rather than skip my break. I alway plan gas station and meal breaks to coincide as well; two birds, you know
It's as much a mental thing as well as physical and safety. Thinking, "Only thirty minutes to the next break," even though it's a whole bunch of times per day, it's a lot easier than, "Five freaking hours until I can quit for the day."
Including the once around the rig and the bathroom if necessary, pour a cup of coffee or grab a soda from the cooler, I'm usually back on the road in around 10-12 minutes. With two axles and four brakes on the trailer, and plenty of tongue weight, on the Interstates my rig is reasonably comfortable and I believe reasonably safe up to 75 mph or so, and if I maintain close to that I can still average 60mph or better over the long haul. Occasionally I'll even grab 30-45 minute nap if I'm not feeling up to being back on the road right away.
I wouldn't try to eat a burger or the like while towing the trailer at speed, so even if it's fast food, lunch is always 30-45 minutes to relax and chill.
This has worked well for me. I'm not kidding when I say stuff normally doesn't go way wrong in an hour, but given much more than that...
During my hourly once around I've discovered 1) a big chunk of rubber missing out of a brand new trailer tire 2) loss of air pressure in the trailer tires caused by nails in the tires (twice; are these things nail magnets?) 3) a dragging halyard 4) an almost dragging backstay, 6) inoperable taillights (this one was at night, and yes, they had been working at the previous hourly check) 5) disconnected emergency brake cable 6) loose lug nuts (numerous times) 7) fender dragging on the tire. In each case, I found it early enough that disaster was avoided.
And once (I regret to confess) "somebody" forgot to latch down the trailer hitch. Found it before it came off the ball and before I got a chance to see if the safety chains worked.