Mike,
I have the exact same motor and the exact same issue. I've been fighting with it all season. Here's what I've done so far - to no avail:
1.) Removed the quick connect from the gas tank and replaced it with a regular, fixed connector.
2.) Cleaned and adjusted the inlet strainer inside my gas tank.
3.) Replaced the primer bulb.
4.) Replaced the low-pressure fuel filter in the DF50.
5.) Purchased but haven't yet installed a new Suzuki fuel-line connector on the DF50 side.
The fuel line itself will be next. Beyond that, I'm out of ideas. I tested for air leaks (my first theory). I always make sure the tank vent is open - even loosen the cap sometimes to be sure. Nothing. It runs for a few minutes then sputters. I've been priming it continuously during use, all summer long. It's embarassing to explain to guests why you're doing it
My boat is back in the driveway now - season's over.

I'll let you know what I find in the fuel line. Beyond that, it'll have to go to the pros ($$$).
Good luck! Let us know what you find.
~Bob